7:00 am - 8:30 am: Breakfast
Calusa Terrace
7:30 am – 3:00 pm: Registration Open
Conference Foyer
8:30 am - 10:30 am
Mechanisms of NK Cell Activation
Estero Ballroom
Moderators:
Eva König, St. Anna Children's Cancer Research Institute
Ana Stojanovic, Heidelberg University
8:30 am – 8:50 am
Megan Cooper, Washington University School of Medicine
8:50 am – 9:10 am
Jordan Orange, Columbia University Medical Center
9:10 am – 9:30 am
Emily Mace, Columbia University Medical Center
9:30 am – 9:50 am
Carsten Watzl, Leibniz Research Center Dortmund
9:50 am – 10:00 am
125 Circulating Natural Killer cells potentiate white adipose tissue inflammation during obesity through XCL1-dependent recruitment of cDC1
Andrew D. Hildreth, UCLA
10:00 am – 10:10 am
126 CD3-zeta adaptor structure determines functional differences between human and mouse CD16 Fc-gamma receptor signaling in natural killer cells
Oscar A. Aguilar, University of California - San Francisco
10:10 am – 10:20 am
127 Genome-Wide CRISPR screen identifies TMEM30A as a key regulator of NK cell cytotoxicity
Linnea Kristenson, University of Gothenburg
10:20 am – 10:30 am
128 A XBP1s-PIM-2 positive feedback loop controls IL-15-mediated survival of natural killer cells
Shoubao Ma, City of Hope National Medical Center
10:00 am – 3:00 pm: Exhibit & Poster Hall Open
Calusa A-E
10:30 am – 11:00 am: Coffee Break
Calusa A-E
11:00 am - 12:30 pm: NK Cells and Cancer II
Estero Ballroom
Moderators:
Camille Guillerey, The University of Queensland
Sandro Matosevic, Purdue University
11:00 am – 11:20 am
David Finlay, Trinity College Dublin
11:20 am – 11:40 am
Silke Paust, Scripps Research
11:40 am – 11:50 am
Cyclic Fasting induces Natural Killer Cell Anti-Tumor Immunity
Rebecca Delconte, Memorial Sloan Kettering Cancer Center
11:50 am - 12:00 pm
Melissa Berrien-Elliott, Washington University School of Medicine
12:00 pm – 12:10 pm
129 Augmenting Chimeric Antigen Receptor NK cell Anti-tumor Activity by Synapse Tuning
Peter Chockley, St Jude Children's Research Hospital
12:10 pm – 12:20 pm
130 Multifunctional Natural Killer Cell Engager Releasing CXCL10 Augments Natural Killer Cell Recruitment and Anti-tumor Efficacy against Glioblastoma
Xue Yao, Purdue University
12:20 pm – 12:30 pm
131 TGFß-imprinting of primary NK cells decreased CD38-NADase, improved cell killing, ADCC and metabolism
Marcelo De Souza Fernandes Pereira, Nationwide Children’s Hospital
12:30 pm – 1:00 pm: Lighting Poster Session II
Estero Ballroom
Moderator:
Laurent Brossay, Brown University
12:30 pm – 12:35 pm
141 HIV-1 mediated downregulation of CD155 impacts the antiviral activity of KIR2DL5+ NK cells
Pia Fittje, Leibniz Institute for Experimental Virology (HPI)
12:35 pm – 12:40 pm
142 NK cell exhaustion: when the serial killer needs to slow down
Kévin Pouxvielh, Sanofi / Inserm U1111 Centre International de Recherche En Infectiologie
12:40 pm – 12:45 pm
143 Single-cell transcriptomics in human bone marrow delineates CD56dimGranzymeK+ subset as intermediate stage in NK cell differentiation
Janine Melsen, Leiden University Medical Center
12:45 pm – 12:50 pm
144 Early life infections extensively reshape the transcriptional profile and functionality of NK cells
Ilija Brizic, Center for Proteomics, Faculty of Medicine, University of Rijeka
12:50 pm – 12:55 pm
145 Primary Human NK Cells Transduced with the High Affinity CD64 Fc Receptor Can Be Successfully Pre-loaded with anti-HIV BNAbs and Trigger Strong ADCC Against HIV-1 Infected Autologous CD4+ Primary T Cells
Costin Tomescu, The Wistar Institute
12:55 pm – 1:00 pm
146 Identification of a soluble NK inhibitory protein of HCMV
Virginia M. Vlachava, Cardiff University
1:00 pm – 3:00 pm: Lunch & Poster Session II: Posters 125 – 243
Calusa Terrace
Calusa A-E
7:00 pm – 10:00 pm: Gala Dinner
Royal Palm Courtyard
Separate Registration Required